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The terms nodule and cyst are often used interchangeably. While both nodules and cysts are similar in physical appearance and are both inflammatory acne lesions, their anatomical structures are different.
NODULAR ACNE: A nodule is an inflammatory lesion that is deep. With a nodule, the bottom of the follicle erupts and the inflammation extends down into the dermis, or even as deep as the subcutaneous fatty layer. A nodule forms a painful lump in the skin, firm to the touch, that can be greater than 0.5 - 1cm in width and in depth.1,2 Nodules may come and go over the course of weeks or even months.3
3. Braun-Falco, Otto; et al. (2000). Dermatology. (2nd Ed.) Springer
The terms nodule and cyst are often used interchangeably. While both nodules and cysts are similar in physical appearance and are both inflammatory acne lesions, their anatomical structures are different.NODULAR ACNE: A nodule is an inflammatory lesion that is deep. With a nodule, the bottom of the follicle erupts and the inflammation extends down into the dermis, or even as deep as the subcutaneous fatty layer. A nodule forms a painful lump in the skin, firm to the touch, that can be greater than 0.5 - 1cm in width and in depth.1,2 Nodules may come and go over the course of weeks or even months.3
CYSTIC ACNE: A cyst is an inflammatory acne lesion that has a sac-like structure formed by epithelial cells. Cysts can develop when several follicles rupture and combine to form one large lesion about the size of the tip of your little finger. Cysts can also develop from severe inflammation of one follicle. Cysts are typically pus filled, made up of cellular debris, white blood cells, oil and bacteria . The contents of a cyst can be liquid, semi-solid, or solid.4 Cysts tend to be 1 to 5cm (yes, centimeters!) in size with a prominent central pore, and are most commonly found behind the ears and along the eyebrows.3
1. Callen, Jeffrey (2000). Color atlas of dermatology. Philadelphia: W.B. Saunders.
2. James, William D.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier.3. Braun-Falco, Otto; et al. (2000). Dermatology. (2nd Ed.) Springer
4. Fitzpatrick, Thomas B.; Klauss Wolff; Wolff, Klaus Dieter; Johnson, Richard R.; Suurmond, Dick; Richard Suurmond (2005). Fitzpatrick's color atlas and synopsis of clinical dermatology. New York: McGraw-Hill Medical Pub. Division.
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